sci.life-extension Google Group

What is Tubal Reversal?

2010-03-11T10:12:05Z

Tubal Reversal is a process for those women who would like to restore
their fertility in order to have more babies. This surgery, also known
as tubal ligation reversal, microsurgical tubal reanastomosis, and
sterilization reversal, is done by opening the previously blocked
fallopian tube so that the egg can be fertilized by the sperm. It is a

Copper toxicity in diabetes

2010-03-11T08:00:49Z

Might pertain to the antidiabetic role of molybdenum and metallothionein
[PMID 18480419, 19324938].
Endocr J. 2009 Oct;56(5):699-706. Epub 2009 May 20.

Role of copper ion in the pathogenesis of type 2 diabetes.
Tanaka A, Kaneto H, Miyatsuka T, Yamamoto K, Yoshiuchi K, Yamasaki Y,
Shimomura I, Matsuoka TA, Matsuhisa M.

Insulin resistance is a cellular antioxidant defense mechanism.

2010-03-11T02:21:46Z

Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17787-92. Epub 2009 Sep
30.
Insulin resistance is a cellular antioxidant defense mechanism.
Hoehn KL, Salmon AB, Hohnen-Behrens C, Turner N, Hoy AJ, Maghzal GJ,
Stocker R, Van Remmen H, Kraegen EW, Cooney GJ, Richardson AR, James
DE.
Diabetes and Obesity Program, Garvan Institute of Medical Research,

Relationship of dietary habits and obesity to oxidative stress in Palauan people: compared with Japanese and Mongolian people

2010-03-11T02:18:41Z

Micronesians now eat a Western style diet. A thin people who's BMIs
increased to an average of 30. This is after a switch from their
traditional diet.
Curr Aging Sci. 2009 Dec;2(3):214-22.
Relationship of dietary habits and obesity to oxidative stress in
Palauan people: compared with Japanese and Mongolian people.

Effects of alpha-lipoic acid on transforming growth factor beta1-p38 mitogen-activated protein kinase-fibronectin pathway in diabetic nephropathy

2010-03-10T21:16:53Z

Metabolism. 2009 May;58(5):616-23.
Effects of alpha-lipoic acid on transforming growth factor beta1-p38
mitogen-activated protein kinase-fibronectin pathway in diabetic
nephropathy.
Lee SJ, Kang JG, Ryu OH, Kim CS, Ihm SH, Choi MG, Yoo HJ, Kim DS, Kim
TW.
Department of Endocrinology and Metabolism, College of Medicine,

Purification and localization of a 25-kD porcine renal puromycin aminonucleoside-binding protein.

2010-03-10T20:15:03Z

Nephrol Dial Transplant. 1997 Jul;12(7):1453-60.
Purification and localization of a 25-kD porcine renal puromycin
aminonucleoside-binding protein.
Kodama T, Wakui H, Komatsuda A, Imai H, Miura AB, Tashima Y.
Third Department of Internal Medicine, Akita University School of
Medicine, Japan.
BACKGROUND: Reactive oxygen species (ROS) are considered to have a

Akt regulates skeletal development through GSK3, mTOR, and FoxOs

2010-03-10T16:40:17Z

Dev Biol. 2009 Apr 1;328(1):78-93. Epub 2009 Jan 14.
Akt regulates skeletal development through GSK3, mTOR, and FoxOs.
Rokutanda S, Fujita T, Kanatani N, Yoshida CA, Komori H, Liu W, Mizuno
A, Komori T.
Department of Cell Biology, Unit of Basic Medical Sciences, Nagasaki
University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto,

signaling patheay for normal maintenance of stem cells.

2010-03-10T16:32:24Z

[link]

FoxO transcription factors promote autophagy in cardiomyocytes.

2010-03-10T16:26:50Z

cellular stress, such as starvation or ischemia/reperfusion in mice,
results in induction of autophagy in the heart with concomitant
dephosphorylation of FoxO, consistent with increased activity of
nuclear FoxO transcription factors. Together these results provide
evidence for an important role for FoxO1 and FoxO3 in regulating

Autophagy is required to maintain muscle mass.

2010-03-10T16:23:55Z

Cell Metab. 2009 Dec;10(6):507-15.
Autophagy is required to maintain muscle mass.
Masiero E, Agatea L, Mammucari C, Blaauw B, Loro E, Komatsu M, Metzger
D, Reggiani C, Schiaffino S, Sandri M.
Dulbecco Telethon Institute, 35129 Padova, Italy.
The ubiquitin-proteasome and autophagy-lysosome pathways are the two

Re: Dermal fibroblasts from long-lived Ames dwarf mice maintain their in vivo resistance to mitochondrial generated reactive oxygen species (ROS).

2010-03-10T16:20:21Z

FULL TEXT
[link]

Dermal fibroblasts from long-lived Ames dwarf mice maintain their in vivo resistance to mitochondrial generated reactive oxygen species (ROS).

2010-03-10T16:18:33Z

Pieces of the puzzle are now so easily plucked thanks to the
divergent and subsequent convergent thinking of experimentalists.
Aging (Albany NY). 2009 Jul 31;1(9):784-802.
Dermal fibroblasts from long-lived Ames dwarf mice maintain their in
vivo resistance to mitochondrial generated reactive oxygen species

Inhibition of p38alpha unveils an AMPK-FoxO3A axis linking autophagy to cancer-specific metabolism.

2010-03-10T16:14:40Z

Autophagy. 2009 Oct;5(7):1030-3. Epub 2009 Oct 12.
Inhibition of p38alpha unveils an AMPK-FoxO3A axis linking autophagy
to cancer-specific metabolism.
Chiacchiera F, Simone C.
Laboratory of Signal-dependent Transcription, Department of
Translational Pharmacology (DTP), Consorzio Mario Negri Sud, Santa

The AMPK-FoxO3A axis as a target for cancer treatment

2010-03-10T16:12:34Z

Cell Cycle. 2010 Mar 22;9(6). [Epub ahead of print]
The AMPK-FoxO3A axis as a target for cancer treatment.
Chiacchiera F, Simone C.
Laboratory of Signal-dependent Transcription, Department of
Translational Pharmacology (DTP), Consorzio Mario Negri Sud, Santa
Maria Imbaro (Chieti), Italy.
FoxO proteins are an evolutionarily conserved subfamily of

Interetsing connection between FOXO3a and Nrf2 ,ARE

2010-03-10T16:09:03Z

[link]